Athymic Nude Rat Brain Atlas

by Bengt Mattsson, Malin Parmar, Anders Björklund, Published: April 2023, FileType: PDF

Athymic Nude Rat Brain Atlas pdf will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a computerized 3D environment. The maps enable readers to better calculate co-ordinates to target specific structures for toxin, virus, or cell delivery using stereotaxic surgery. This atlas will be a valuable resource for any neuroscientist who wishes to work with nude rats in experimental and pre-clinical studies.

Read More: MRI/DTI Atlas of the Rat Brain

• Contains coronal, sagittal, and horizontal maps of young adult athymic nude rat brain, spaced with a distance of 0.2 or 0.25 mm
• Uses “flat skull” Bregma and Lambda as anatomical landmarks for correct placement in the 3D environment
• Anatomical structures and nomenclature follow the standard set by the Paxinos and Watson rat brain atlases
• Includes a map of the dopamine projection system as well as the distribution of the A8-A14 dopamine cell groups
• Allows for easy read-out of coordinates for precise injections using stereotactic surgery

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