Handbook of Laboratory Animal Anesthesia and Pain Management: Rodents. Rodents are the most commonly used species in biomedical research. Individuals conducting rodent research are often responsible to ensure that all areas of anesthesia and analgesia are performed humanely.

Handbook of Laboratory Animal Anesthesia and Pain Management: Rodents

Anesthetic agent selection, anesthetic monitoring, and postoperative pain assessment and management are essential to the institutional animal care and use program and contribute significantly to the 3Rs by reducing pain and/or distress and refining various procedures.

The Handbook of Laboratory Animal Anesthesia and Pain Management: Rodents is the first book to capture multiple advances in this important area that greatly impacts various experimental methodologies. Richly illustrated in full color, the book serves as a quick reference source for investigators, veterinarians, technicians, and other animal caretakers charged with the care and use of rodents in a research setting. The unique format of this book also makes it extremely valuable to IACUC members, institutional officials, and occupational health and safety professionals.

This handbook is organized into nine chapters: (1) terms and definitions; (2) understanding anesthetic-related equipment; (3) anesthetic pharmacology and research-related anesthetic considerations; (4) management of anesthesia; (5) anesthetic monitoring; (6) special techniques and species; (7) pain management; (8) euthanasia; and (9) regulatory management of rodent anesthesia. Basic information and common procedures are presented in detail. Other information regarding alternative techniques and details of procedures and methods beyond the scope of this handbook is referenced extensively, so users are directed toward additional information without having to wade through a burdensome volume of detail. In this sense, this handbook should be viewed as a basic reference source and not as an exhaustive review of rodent anesthesia and pain management.

A final point for consideration is that all individuals performing procedures requiring anesthesia and analgesia must be properly trained. The humane care and use of rodents is improved by initial and continued education of personnel and will facilitate the overall process of programs using rodents in research, teaching, and testing.

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